Preheat oven to 350° F. Grease and flour 9 x 5" metal loaf pan.
Stir flour, baking powder, baking soda, and salt together in a medium bowl.
Mix butter on a low speed until smooth. Add sugar and beat until creamy at medium-high speed. Beat in vanilla.
Reduce speed to low and add eggs, one at a time, beating after each addition until well blended. Scrape bowl occasionally as needed. Add flour mixture alternately with sour cream, beginning and ending with flour mixture. Fold in blueberries.